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Table 4 Univariable and multivariable regression analyses of longitudinal PDSR

From: Effect of glycemic status on myocardial deformation and microvascular function in uncomplicated pediatric type 1 diabetes mellitus: cardiac magnetic resonance imaging

Variables

Univariable

Multivariablea

Multivariableb

β (95% CI)

p

β (95% CI)

t

p

β (95% CI)

t

p

Age

− 0.03 (− 0.05 to − 0.01)

0.005

      

Female

− 0.01 (− 0.14 to 0.11)

0.829

      

BMI

0.00 (− 0.02 to 0.02)

0.912

0.02 (0.01 to 0.03)

2.22

0.030

   

BSA

− 0.12 (− 0.33 to 0.08)

0.250

      

SBP

− 0.01 (− 0.99 to − 0.01)

0.035

− 0.01 (− 0.99 to − 0.01)

− 2.53

0.014

   

DBP

− 0.00 (− 0.01 to 0.00)

0.146

      

Waist-to-hip ratio

0.38 (− 0.20 to 0.95)

0.203

      

Age at diagnosis

− 0.02 (− 0.03 to − 0.01)

0.005

      

Duration (years)

0.01 (− 0.01 to 0.02)

0.196

      

HbA1c

− 0.31 (− 0.45 to − 0.16)

 < 0.001

− 0.02 (− 0.04 to − 0.01)

− 2.80

0.007

   

FBG

− 0.01 (− 0.02 to 0.01)

0.354

      

TC

− 0.03 (− 0.08 to 0.01)

0.136

      

TG

− 0.04 (− 0.08 to − 0.01)

0.022

      

HDL

0.02 (− 0.09 to 0.12)

0.772

      

LDL

− 0.02 (− 0.07 to 0.03)

0.369

   

− 0.11 (− 0.19 to − 0.03)

− 2.67

0.013

ApoA1

0.03 (− 0.15 to 0.20)

0.766

      

Urea Nitrogen

0.01 (− 0.03 to 0.04)

0.754

      

Creatinine

− 0.00 (− 0.01 to 0.00)

0.254

      

Uric Acid

0.00 (− 0.00 to 0.00)

0.336

      

Cystatin C

0.09 (− 0.27 to 0.45)

0.622

      

Upslope

0.12 (0.05 to 0.19)

 < 0.001

   

0.10 (0.02 to 0.18)

2.59

0.016

MaxSI

0.01 (− 0.00 to 0.02)

0.167

   

− 0.02 (− 0.03 to − 0.01)

− 3.03

0.006

  1. Candidate variables for multivariable models were selected based on clinical backgrounds and the absence of collinearity
  2. The variable “age at diagnosis” was excluded from multivariable analysis because of collinearity
  3. aVariables with p < 0.1 and based on clinical backgrounds and the absence of collinearity were included in the multivariable analysis
  4. bPerfusion parameters were added as covariates in the multivariable analysis
  5. PDSR peak diastolic strain rate; Max SI maximal signal intensity, CI confidential interval. Other abbreviations are the same as in Table 1