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Table 3 The association of TyG, TyG-BMI, TyG-WC and TyG-WHtR and heart diseas in non-T2D patients

From: The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national cohort study

Variable

n. %

Without T2D

Model 1

Model 2

Model 3

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

TyG

1245 (18.2)

1.08 (1.01–1.15)

0.029

1.05 (0.98–1.12)

0.146

1.04 (0.97–1.12)

0.239

Quartile

 Q1

312 (16.1)

1(Ref)

 

1(Ref)

 

1(Ref)

 

 Q2

333 (18.1)

1.10 (0.94–1.28)

0.237

1.07 (0.91–1.25)

0.404

1.05 (0.9–1.23)

0.532

 Q3

344 (19.9)

1.18 (1.01–1.37)

0.04

1.15 (0.98–1.34)

0.088

1.12 (0.96–1.31)

0.163

 Q4

256 (19.2)

1.18 (1.01–1.4)

0.048

1.12 (0.94–1.32)

0.205

1.09 (0.92–1.30)

0.304

P for trend

  

0.026

 

0.122

 

0.204

TyG-BMI

1245 (18.2)

1.22 (1.15–1.29)

< 0.001

1.19 (1.13–1.26)

< 0.001

1.18 (1.12–1.26)

< 0.001

Quartile

 Q1

273 (14.5)

1(Ref)

 

1(Ref)

 

1(Ref)

 

 Q2

312 (17.3)

1.26 (1.07–1.48)

0.006

1.27 (1.07–1.49)

0.005

1.26 (1.06–1.48)

0.007

 Q3

318 (18.5)

1.35 (1.14–1.59)

< 0.001

1.35 (1.14–1.59)

< 0.001

1.33 (1.12–1.57)

0.001

 Q4

342 (23.8)

1.83 (1.55–2.16)

< 0.001

1.75 (1.47–2.08)

< 0.001

1.72 (1.44–2.05)

< 0.001

P for trend

  

< 0.001

 

< 0.001

 

< 0.001

TyG-WC

1245 (18.2)

1.19 (1.11–1.26)

< 0.001

1.16 (1.08–1.23)

< 0.001

1.15 (1.07–1.22)

< 0.001

Quartile

       

 Q1

281 (14.9)

1(Ref)

 

1(Ref)

 

1(Ref)

 

 Q2

309 (16.9)

1.15 (0.98–1.35)

0.093

1.15 (0.98–1.35)

0.094

1.14 (0.97–1.34)

0.121

 Q3

337 (19.5)

1.33 (1.13–1.56)

< 0.001

1.31 (1.12–1.54)

0.001

1.29 (1.1–1.52)

0.002

 Q4

318 (22.7)

1.58 (1.35–1.86)

< 0.001

1.47 (1.24–1.75)

< 0.001

1.44 (1.22–1.71)

< 0.001

P for trend

  

< 0.001

 

< 0.001

 

< 0.001

TyG-WHtR

1245 (18.2)

1.15 (1.08–1.23)

< 0.001

1.11 (1.04–1.19)

0.001

1.10 (1.03–1.18)

0.004

Quartile

 Q1

280 (14.9)

1(Ref)

 

1(Ref)

 

1(Ref)

 

 Q2

315 (17.3)

1.14 (0.97–1.34)

0.109

1.13 (0.96–1.32)

0.156

1.12 (0.95–1.32)

0.186

 Q3

316 (18.4)

1.17 (1–1.38)

0.056

1.12 (0.95–1.33)

0.166

1.10 (0.93–1.31)

0.246

 Q4

334 (23.5)

1.45 (1.23–1.72)

< 0.001

1.34 (1.13–1.60)

0.001

1.31 (1.10–1.57)

0.002

P for trend

  

< 0.001

 

0.002

 

0.005

  1. Per SD increased of TyG, TyG-BMI, TyG-WC, Ty G-WHtR as continuous variable. SD: standard deviation
  2. Model 1 adjusted for age, sex, marital status, rural
  3. Model 2 adjusted for Model 1 + smoke, drink, WBC, platelet, HGB, cancer, lung disease, stroke, liver disease, renal disease, digestive disease, asthma, hypertension
  4. Model 3 adjusted for Model3 + LDL, HbA1c, pulse
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Cardiovascular Diabetology

ISSN: 1475-2840